Monday, July 17, 2017

Spectrum Pharmaceuticals: Will Rolontis Substantially Increase Prospects?


  • Fusilev delivered opportunistic growth for Spectrum but earnings are now dependent on the six approved cancer drugs.
  • Despite lackluster sales, approved therapeutics generate meaningful incomes to fund further innovation.
  • Developing molecules (poziotinib and Rolontis) are likely to post positive data (and to deliver significant sales).

During the 2009 to 2012 leucovorin shortage, shares of Spectrum Pharmaceuticals (NASDAQ:SPPI) (a firm that focuses on the development and commercialization of drugs to treat blood disorders and cancers) soared from $5 to $17 peak. The company's lead drug, Fusilev, a pure racemic form of leucovorin, is used as a folate analog for methotrexate rescue therapy. It is also indicated in combinations with 5-fluorouracil for the palliative management of advanced metastatic colorectal cancer.

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